January 19, 2021

High-throughput glycomic analyses reveal unique oligosaccharide profiles of canine and feline milk samples

Oligosaccharides are necessary parts of milk, serving as substrates for the intestinal microbiota, performing as antimicrobials that forestall pathogen colonization, and supporting the growing gastrointestinal immune system of neonates. Nutrient composition of canine and feline milk samples has been described beforehand, however little is understood concerning the oligosaccharide content material. Subsequently, the target of this examine was to characterize canine and feline milk samples utilizing a high-throughput glycomics strategy.

23 canines (9 Labrador retriever and 14 Labrador retriever x golden retriever crossbreed) and 6 home shorthair cats had been recruited to the examine. Milk samples had been collected by guide expression at time factors after parturition. Samples had been collected throughout 2 phases per species, differentiated by maternal weight loss program. Following extraction, oligosaccharide content material was decided by liquid chromatography-mass spectrometry (LC-MS). In canine milk samples, Three buildings accounted for over 90% of all oligosaccharides detected throughout two weight loss program teams. These had been 3′-sialyllactose, 6′-sialyllactose, and a couple of’-fucosyllactose. In feline samples, a extra numerous vary of oligosaccharides was detected, with as much as 16 buildings current at relative abundance >1% of the full. Difucosyllactose-N-hexaose b, 3′-sialyllactose and lacto-N-neohexaose had been all detected at abundances >10% in feline milk samples.

Statistically vital variations (p<0.05) in oligosaccharide abundances had been noticed between assortment time factors and between weight loss program teams inside species. These information discover the oligosaccharide content material of canine and feline maternal milk, representing a possibility to generate a elementary understanding of the dietary wants of new-born puppies and kittens. Anatomic pathology is an important part of veterinary medication however as a primarily subjective qualitative or semiquantitative self-discipline, it’s susceptible to cognitive biases. Logistic regression is a statistical method used to clarify relationships between information classes and outcomes and is more and more being utilized in medication for predicting illness chance based mostly on medical and affected person variables.

A assessment of the efficacy of a low-cost most cancers screening check utilizing most cancers sniffing canines

One of the crucial highly effective instruments in combating most cancers is early detection, because it has been strongly linked to better possibilities of most cancers survival. Nevertheless, conventional most cancers screening assessments can price a whole lot if not 1000’s of {dollars} and are due to this fact not an reasonably priced choice for a lot of marginalized populations. From a public well being perspective, it’s vital to analysis using cheap most cancers detection in order that low-resourced sufferers have better entry to reasonably priced most cancers screening. Quite a few research relationship from the early 2000s to current years have proven intensive proof that the distinctive olfactory system of canines permits them to detect sure odors by way of exhaled breath condensate which are recognized to be biomarkers of a wide range of cancers.
Along with offering a less expensive different to standard most cancers screening assessments, using most cancers sniffing canines has different advantages, together with nice reliability and accuracy. There are just a few main varieties of most cancers for which the “most cancers canine check” proved to be remarkably efficient, significantly colorectal, ovarian, and lung cancers. The check is non-invasive not like most earlier detection strategies, that means that it’s also a safer choice for people looking for most cancers screening. Though using most cancers sniffing canines does have sure limitations and scope for error, it will present a extra reasonably priced and accessible choice for most cancers screening, making it particularly helpful to low-resourced populations.

CNTNAP1 Missense Variant Is Related to Canine Laryngeal Paralysis and Polyneuropathy

Laryngeal paralysis related to a generalized polyneuropathy (LPPN) mostly exists in geriatric canines from a wide range of giant and big breeds. The aim of this examine was to find the underlying genetic and molecular mechanisms in a younger-onset type of this neurodegenerative illness seen in two carefully associated big canine breeds, the Leonberger and Saint Bernard.
Neuropathology of an affected canine from every breed confirmed variable nerve fiber loss and scattered inappropriately skinny myelinated fibers. Utilizing across-breed genome-wide affiliation, haplotype evaluation, and whole-genome sequencing, we recognized a missense variant within the CNTNAP1 gene (c.2810G>A; p.Gly937Glu) through which homozygotes in each studied breeds are affected. CNTNAP1 encodes a contactin-associated protein necessary for group of myelinated axons. The herein described probably pathogenic CNTNAP1 variant happens in unrelated breeds at variable frequencies. Particular person homozygous mutant LPPN-affected Labrador retrievers that had been on common 4 years youthful than canines affected by geriatric onset laryngeal paralysis polyneuropathy could possibly be defined by this variant.
Canine Parvovirus protein
30-1254 1 mg
EUR 457
Description: Purified Native Canine Parvovirus protein
Mouse antibody for Canine Parvovirus
7341 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against Canine Parvovirus for WB, ELISA.
Mouse antibody for Canine Parvovirus
7351 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against Canine Parvovirus for WB, ELISA.
Canine parvovirus ELISA Kit
QY-E70086 96T
EUR 426
Inactivated Canine Parvovirus Antigen
VAng-Lsx0420-1mg 1 mg
EUR 1138
Description: Canine parvovirus protein, native protein from CRFK cells.
Mouse Anti-Canine Parvovirus monoclonal antibody
CABT-BL8719 1.0 mg
EUR 892
Mouse Anti-Canine Parvovirus monoclonal antibody
CABT-BL8720 1.0 mg
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Mouse Anti-Canine Parvovirus monoclonal antibody
CABT-BL8721 1.0 mg
EUR 892
Canine/Feline Parvovirus (FCV/CPV) Antibody
abx413670-025mg 0.25 mg
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  • Shipped within 1 week.
Mouse Anti-Canine Parvovirus Monoclonal Antibody
DMAB4049 1 mg
EUR 903
Mouse Anti-Canine Parvovirus Monoclonal Antibody
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Mouse Anti Canine Parvovirus Monoclonal Antibody
DMABT-51142MC 0.1 mg
EUR 767
Mouse Anti Canine Parvovirus Monoclonal Antibody
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Canine parvovirus IgG ELISA Kit
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Canine parvovirus,CPV ELISA Kit
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EUR 426
Canine parvovirus type 2 PCR kit
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EUR 425.8
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Canine parvovirus type 2 PCR kit
PCR-V080-96D 100T
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Description: An conventional PCR kit for detection of Canine parvovirus type 2
ELISA kit for Canine Parvovirus (CPV)  Kit
KTE20151-48T 48T
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Description: Quantitative sandwich ELISA for measuring Canine Parvovirus (CPV)  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Canine Parvovirus (CPV)  Kit
KTE20151-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Canine Parvovirus (CPV)  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Canine Parvovirus (CPV)  Kit
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Canine parvovirus type 2 RT PCR kit
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Canine parvovirus type 2 RT PCR kit
RTq-V080-150D 150T
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Canine parvovirus type 2 RT PCR kit
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EUR 532.8
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Parvovirus antibody
10-7875 1 mg
EUR 424
Description: Mouse monoclonal Antibody raised against Parvovirus
Parvovirus antibody
10-7876 1 mg
EUR 424
Description: Mouse monoclonal Antibody raised against Parvovirus
Parvovirus antibody
10-P59A 1 mg
EUR 424
Description: Mouse monoclonal Antibody raised against Parvovirus
Parvovirus antibody
10-P59B 1 mg
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Description: Mouse monoclonal Antibody raised against Parvovirus
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abx092032-40tests 40 tests
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Canine parvovirus type 2 One-Step PCR kit
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Canine parvovirus type 2 One-Step PCR kit
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Parvovirus B19 Antibody
abx023653-1mg 1 mg
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Feline Parvovirus Antigen
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Pig Parvovirus Antibody ELISA Kit
abx364911-96tests 96 tests
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Mouse antibody for Parvovirus B19
5191 100 ug
EUR 321.88
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Anti-Human Parvovirus B19 antibody
STJ16100413 1 mL
EUR 826
Recombinant Parvovirus Parvovirus VP2 protein Protein, Native, Human-100ug
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Recombinant Parvovirus Parvovirus VP2 protein Protein, Native, Human-2mg
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Pig Parvovirus Antibody Rapid Test Kit
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Mouse Anti Parvovirus B19 Monoclonal Antibody
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ELISA kit for Pig Parvovirus Antibody
KTE80232-48T 48T
EUR 387
  • Porcine parvovirus (PPV) causes reproductive failure of swine characterized by embryonic and fetal infection and death, usually in the absence of outward maternal clinical signs. The disease develops mainly when seronegative dams are exposed oronasal
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Description: Quantitative sandwich ELISA for measuring Pig Parvovirus Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Pig Parvovirus Antibody
KTE80232-5platesof96wells 5 plates of 96 wells
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  • Porcine parvovirus (PPV) causes reproductive failure of swine characterized by embryonic and fetal infection and death, usually in the absence of outward maternal clinical signs. The disease develops mainly when seronegative dams are exposed oronasal
  • Show more
Description: Quantitative sandwich ELISA for measuring Pig Parvovirus Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Pig Parvovirus Antibody
KTE80232-96T 96T
EUR 680
  • Porcine parvovirus (PPV) causes reproductive failure of swine characterized by embryonic and fetal infection and death, usually in the absence of outward maternal clinical signs. The disease develops mainly when seronegative dams are exposed oronasal
  • Show more
Description: Quantitative sandwich ELISA for measuring Pig Parvovirus Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Parvovirus B19 VP2 Protein
abx061460-1mg 1 mg
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Parvovirus B19 NS1 Protein
abx061544-1mg 1 mg
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Parvovirus B19 VP1 Protein
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Parvovirus B19 Vp1 Protein
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Parvovirus B19 VP1 Protein
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Parvovirus B19 VP1 Protein
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Parvovirus B19 VP2 Protein
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Parvovirus VLP VP1 Protein
20-abx260309
  • EUR 885.00
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Parvovirus IgG ELISA kit
55R-IB79806 96 wells
EUR 690
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Parvovirus IgM ELISA kit
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Parvovirus В19 PCR kit
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Parvovirus В19 PCR kit
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Goose parvovirus PCR kit
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EUR 425.8
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Goose parvovirus PCR kit
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Porcine parvovirus PCR kit
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Description: An conventional PCR kit for detection of Porcine parvovirus
Porcine parvovirus PCR kit
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Bovine parvovirus PCR kit
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EUR 425.8
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Bovine parvovirus PCR kit
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Inactivated Feline Parvovirus Antigen
VAng-Lsx0419-1mg 1 mg
EUR 1138
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Recombinant Parvovirus VP2 Protein
VAng-Lsx0422-inquire inquire Ask for price
Description: Parvovirus VP2, recombinant protein from Baculovirus.
Dog parvovirus (PV) antibody (IgG) ELISA kit
CSB-EQ027717DO-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Qualitativeindirect ELISA kit for measuring Dog parvovirus (PV) antibody (IgG) in samples from serum. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Dog parvovirus (PV) antibody (IgG) ELISA kit
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  • EUR 703.00
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  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Qualitativeindirect ELISA kit for measuring Dog parvovirus (PV) antibody (IgG) in samples from serum. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Mouse parvovirus (PV) antibody (IgG) ELISA kit
CSB-EQ027717MO-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Mouse parvovirus (PV) antibody (IgG) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Mouse parvovirus (PV) antibody (IgG) ELISA kit
1-CSB-EQ027717MO
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Mouse parvovirus (PV) antibody (IgG) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Pig parvovirus (PV) antibody (IgG) ELISA kit
CSB-EQ027717PI-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Pig parvovirus (PV) antibody (IgG) in samples from serum. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Pig parvovirus (PV) antibody (IgG) ELISA kit
1-CSB-EQ027717PI
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Pig parvovirus (PV) antibody (IgG) in samples from serum. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
ELISA kit for Goat Parvovirus Antibody  Kit
KTE50035-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Goat Parvovirus Antibody  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Goat Parvovirus Antibody  Kit
KTE50035-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Goat Parvovirus Antibody  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Goat Parvovirus Antibody  Kit
KTE50035-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Goat Parvovirus Antibody  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Mouse Parvovirus (PV) ELISA Kit
abx055037-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.
Dog Parvovirus (PV) ELISA Kit
abx055581-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.
Human Parvovirus (PV) ELISA Kit
abx055724-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.
Parvovirus B19 VP1/VP2 Protein
abx061565-1mg 1 mg
EUR 2778
  • Shipped within 5-10 working days.
Parvovirus B19 VLP VP2 Protein
20-abx262033
  • EUR 4490.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug
  • Shipped within 5-10 working days.
Porcine parvovirus Capsid protein VP1
1-CSB-MP323858PQB
  • EUR 389.00
  • EUR 1394.00
  • EUR 563.00
  • EUR 1025.00
  • 100ug
  • 1MG
  • 200ug
  • 500ug
  • MW: 26.4 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Porcine parvovirus Capsid protein VP1,partial expressed in Mammalian cell
Porcine parvovirus Capsid protein VP1
1-CSB-EP323858PQB
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 26.1 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Porcine parvovirus Capsid protein VP1,partial expressed in E.coli
ELISA kit for Mouse Parvovirus
KTE71611-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Mouse Parvovirus in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Parvovirus
KTE71611-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Mouse Parvovirus in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Parvovirus
KTE71611-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Mouse Parvovirus in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Rat Parvovirus
KTE101135-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Rat Parvovirus in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Rat Parvovirus
KTE101135-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Rat Parvovirus in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Rat Parvovirus
KTE101135-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Rat Parvovirus in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Parvovirus В19 RT PCR kit
RTq-H455-100D 100T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Parvovirus В19 .
Parvovirus В19 RT PCR kit
RTq-H455-150D 150T
EUR 701
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Parvovirus В19 .
Parvovirus В19 RT PCR kit
RTq-H455-50D 50T
EUR 532.8
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Parvovirus В19 .
Goose parvovirus RT PCR kit
RTq-V027-100D 100T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Goose parvovirus .
Goose parvovirus RT PCR kit
RTq-V027-150D 150T
EUR 701
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Goose parvovirus .
Goose parvovirus RT PCR kit
RTq-V027-50D 50T
EUR 532.8
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Goose parvovirus .
Porcine parvovirus RT PCR kit
RTq-V122-100D 100T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Porcine parvovirus .
Porcine parvovirus RT PCR kit
RTq-V122-150D 150T
EUR 701
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Porcine parvovirus .
Porcine parvovirus RT PCR kit
RTq-V122-50D 50T
EUR 532.8
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Porcine parvovirus .
Bovine parvovirus RT PCR kit
RTq-V730-100D 100T
EUR 628.5
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Bovine parvovirus .
Bovine parvovirus RT PCR kit
RTq-V730-150D 150T
EUR 701
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Bovine parvovirus .
Bovine parvovirus RT PCR kit
RTq-V730-50D 50T
EUR 532.8
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Bovine parvovirus .
Recombinant Parvovirus NS1 Protein (B19)
VAng-Lsx0431-inquire inquire Ask for price
Description: Parvovirus NS1 (B19), recombinant prottein from E. coli.
Recombinant Parvovirus B19 VP2 VLPs
VAng-Lsx0437-inquire inquire Ask for price
Description: Parvovirus B19 VP2 VLPs, recombinant protein from Sf9.
Magic™ Anti-Parvovirus Monoclonal antibody, Clone N29723QW2
DCABY-4590 1 mg
EUR 962
Magic™ Anti-Parvovirus Monoclonal antibody, Clone N29723QW3
DCABY-4591 1 mg
EUR 962
Canine Heartworm Antibody
abx021749-1mg 1 mg
EUR 662
  • Shipped within 5-10 working days.
Canine Heartworm Antibody
abx022994-1mg 1 mg
EUR 411
  • Shipped within 5-10 working days.
Canine Heartworm antibody
10C-CR1293M2 100 ug
EUR 220
Description: Mouse monoclonal Canine Heartworm antibody
Canine Heartworm antibody
10-1719 100 ug
EUR 358
Description: Mouse monoclonal Canine Heartworm antibody
Canine Heartworm antibody
10-1720 100 ug
EUR 358
Description: Mouse monoclonal Canine Heartworm antibody
Canine Heartworm antibody
10-1721 100 ug
EUR 358
Description: Mouse monoclonal Canine Heartworm antibody
Thyroxine antibody (Canine)
10-T33A 1 mg
EUR 177
Description: Mouse monoclonal Thyroxine antibody (Canine)
Canine Albumin Antibody
12105-05011 150 ug
EUR 217
Canine Apotransferrin Antibody
14078-05011 150 ug
EUR 217
Canine Haptoglobin Antibody
15551-05011 150 ug
EUR 217
Pathologic adjustments in a Labrador retriever nerve biopsy from a homozygous mutant canine had been much like these of the Leonberger and Saint Bernard. The impression of this variant on well being in English bulldogs and Irish terriers, two breeds with increased CNTNAP1 variant allele frequencies, stays unclear. Pathogenic variants in CNTNAP1 have beforehand been reported in human sufferers with deadly congenital contracture syndrome and hypomyelinating neuropathy, together with vocal twine palsy and extreme respiratory misery. That is the primary report of contactin-associated LPPN in canines characterised by a deleterious variant that most definitely predates trendy breed institution.

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